Megetra 40mg Tablet is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV. Megetra 40mg Tablet should be taken with or without food, preferably at a fixed time each day to ensure consistent levels of medicine in the body. This medicine is not used for pregnant or breastfeeding women. It may cause side effects like high blood pressure and increased blood sugar levels but they are temporary. However, if these persist, consult with the doctor.
Written by: Syeda Jigni Mehraj, B pharmacy
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 24-06-2025
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Megetra 40mg Tablet is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV. Megetra 40mg Tablet should be taken with or without food, preferably at a fixed time each day to ensure consistent levels of medicine in the body. This medicine is not used for pregnant or breastfeeding women. It may cause side effects like high blood pressure and increased blood sugar levels but they are temporary. However, if these persist, consult with the doctor.
Breast cancer / Endometrial cancer
In Breast cancer Megetra 40mg Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth. In Endometrial cancer Megetra 40mg Tablet is a synthetic hormone which replicates the effect of a natural female hormone called progesterone. It relieves the symptoms of endometrial cancer (a type of cancer that develops in the lining of the womb) such as, abnormal vaginal bleeding, lower back pain, pain during sex, etc. It interferes with the production and working of those hormones in the body that are essential for the growth and spread of endometrial cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Weight gain, Hot flashes, High blood pressure, Constipation, Increased glucose level in blood']
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Megetra 40mg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.
Megetra 40mg Tablet is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.
Alcohol
Consult your Doctor: Please consult your doctor regarding the safety of consuming alcohol with Megetra 40mg Tablet . Experts have not found evidence of alcohol impairing the effectiveness of the medicine.
Pregnancy
Not Safe: Megetra 40mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
Seek medical advice from your doctor: Megetra 40mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE - Megetra 40mg Tablet does not usually affect your ability to drive.
Kidney
Caution Advised: Megetra 40mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Megetra 40mg Tablet may be needed. Doctor consultation is advised.
Liver
Caution Advised: Megetra 40mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Megetra 40mg Tablet may be needed. Doctor consultation is advised.
Store in a cool and dry place, and keep the temperature below 30�C
Megetra 40 Tablet is used to treat women with certain hormone-dependent cancers such as breast cancer and endometrial cancer. It may also be used for treating appetite and weight loss in people with advanced cancer or AIDS. You may have to take it for atleast 2 months before you notice any changes in your appetite. Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine. Do not take Megetra 40 Tablet if you are pregnant or breastfeeding. Inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein. Do not stop taking the medicine suddenly without talking to your doctor first.
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