Obewist 5 Tablet is used in alone or in combination therapy to treat primary biliary cirrhosis. It helps improve the liver function by inhibiting the production of bile acid and increasing the removal of bile acid from the liver. This reduces the bile acid in the liver and hence prevents its toxic effects.Obewist 5 Tablet�may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it.�You should always complete the full course of the medicine as prescribed by your doctor. Do not stop taking it until you have finished.The most common side effects of this medicine include itching, fatigue, rash, throat pain, dizziness, constipation, joint pain, eczema, and thyroid disorders. If you experience any of these side effects that does not resolve on its own or get worse, you should let your doctor.Before�taking the medicine, tell your doctor if you have any other medical conditions. You should also let your�doctor�know about all the other medicines you are taking (if any), as they may affect or be affected by this medicine. Consult your doctor before using this medicine if you are pregnant or breastfeeding.
Written by: Syeda Jigni Mehraj, B pharmacy
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 24-06-2025
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Obewist 5 Tablet is used in alone or in combination therapy to treat primary biliary cirrhosis. It helps improve the liver function by inhibiting the production of bile acid and increasing the removal of bile acid from the liver. This reduces the bile acid in the liver and hence prevents its toxic effects.Obewist 5 Tablet�may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it.�You should always complete the full course of the medicine as prescribed by your doctor. Do not stop taking it until you have finished.The most common side effects of this medicine include itching, fatigue, rash, throat pain, dizziness, constipation, joint pain, eczema, and thyroid disorders. If you experience any of these side effects that does not resolve on its own or get worse, you should let your doctor.Before�taking the medicine, tell your doctor if you have any other medical conditions. You should also let your�doctor�know about all the other medicines you are taking (if any), as they may affect or be affected by this medicine. Consult your doctor before using this medicine if you are pregnant or breastfeeding.
Treatment of Primary biliary cirrhosis
In Treatment of Primary biliary cirrhosis : Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Obewist 5 Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, it is likely that you will be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.
Side effects of Obewist Tablet The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Obewist Throat pain Itching Fatigue Abdominal discomfort Rash Joint pain Oropharyngeal pain Dizziness Constipation Peripheral edema Palpitations Fever Thyroid disorders
How to use Obewist Tablet Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Obewist 5 Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.
How Obewist Tablet works Obewist 5 Tablet stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obewist 5 Tablet inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.
Alcohol
Consult your Doctor: Please consult your doctor regarding the safety of consuming alcohol with Obewist 5 Tablet . Experts have not found evidence of alcohol impairing the effectiveness of the medicine.
Pregnancy
Information regarding the use of Obewist 5 Tablet during pregnancy is not available. Doctor consultation is advised.
Breast feeding
Information regarding the use of Obewist 5 Tablet during breastfeeding is not available. Doctor consultation is advised.
Driving
It is not known whether Obewist 5 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
Obewist 5 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Obewist 5 Tablet may not be needed in these patients. Doctor consultation is advised.
Liver
Obewist 5 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Obewist 5 Tablet may be needed. Doctor consultation is advised.
If you forget a dose of Obewist 5 Tablet , simply continue with your regular schedule and do not take a double dose.
Store in a cool and dry place, and keep the temperature below 30�C
Obewist 5 Tablet is used for the treatment of primary biliary cirrhosis. Your liver function will be monitored closely while on treatment with Obewist 5 Tablet. Eat a well-balanced diet and indulge in some sort of physical activity daily in order to reduce fatigue and improve well-being. Itching is one of the common side effects of Obewist 5 Tablet. Follow these tips to manage itching:a) Keeping cool will also tend to reduce itch, compared to being warm. Cool showers or cold flannels may be helpful.b)Dry skin can make the itch worse, so using liberal amounts of moisturizer is useful if you have dry skin.c) Do not scratch as scratching will generally make it worse. If scratching is irresistible it may help to rub the itchy area with an ice cube.
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