S Max 5mg Tablet 10s

NULL is a prescription medication that belongs to the class of calcium channel blockers. It is unique because it contains only the S-isomer of amlodipine, the part of the molecule responsible for lowering blood pressure. In standard amlodipine, the R-isomer is largely inactive. By using only the active S-isomer, NULL can provide the same blood pressure-lowering benefits at a lower dose.

The medicine works by blocking calcium from entering the smooth muscle cells of blood vessels, which helps the arteries relax and widen. This vasodilation reduces the resistance the heart has to work against, lowering blood pressure and improving blood flow.

NULL is intended for long-term cardiovascular management. Its long half-life helps maintain stable levels in the bloodstream, supporting consistent blood pressure control with once-daily dosing. Compared to some other calcium channel blockers, it is generally associated with a lower risk of ankle swelling (peripheral edema).

By combining effectiveness with better tolerability, NULL is designed to help patients maintain healthy blood pressure and reduce the risk of complications such as heart attack, stroke, and heart failure.

Hypertension

Treatment of high blood pressure to prevent long-term heart and kidney damage.

Chronic Stable Angina

Management of chest pain caused by reduced blood flow to the heart muscle.

Vasospastic Angina

Treatment of Prinzmetal’s or variant angina caused by coronary artery spasms.

Coronary Artery Disease

Used in patients with documented CAD to reduce the risk of hospitalization for angina.

Effective Pressure Control

Helps maintain blood pressure within a healthy range to reduce the risk of stroke.

Improved Tolerability

Purified S-isomer formulation often results in less swelling than standard versions.

Stable 24-Hour Coverage

Long-acting formula prevents dangerous "spikes" in blood pressure throughout the day.

Heart Protection

Reduces the cardiac workload, allowing the heart to pump more efficiently.

Metabolic Neutrality

Generally does not interfere with blood sugar or cholesterol levels in diabetic patients.

Lower Dose Requirement

Achieves the same clinical result with half the milligrams of regular amlodipine.

Sustained Symptom Relief

Provides consistent relief from chest pain and tightness during physical activity.

Like all medications, NULL may cause side effects. Not everyone experiences them, and many are mild and manageable.

Common Side Effects

• Headache

• Dizziness

• Fatigue

• Nausea

• Facial flushing

• Ankle swelling (Pedal edema)

• Palpitations (racing heart)

Uncommon Side Effects

• Blurred vision

• Tremors

• Constipation or indigestion

• Muscle cramps

• Gingival hyperplasia (gum swelling)

• Orthostatic hypotension (drop in blood pressure when standing)

Serious Side Effects (Seek Immediate Medical Attention)

• Severe Allergic Reaction: Rash, swelling of the face or throat, difficulty breathing.

• Worsening Angina: Sudden or severe chest pain after starting the medication.

• Extreme Hypotension: Fainting or severe lightheadedness.

• Jaundice: Yellowing of the eyes or skin.

• Severe Heart Palpitations: Irregular or pounding heartbeats that do not subside.

NULL should be taken exactly as prescribed by your doctor. It is typically taken once daily and can be taken with or without food. Swallow the tablet whole with a glass of water. It is important to take the medication at the same time every day to maintain a steady level in your system. Do not stop taking this medication suddenly, even if you feel better; doing so can cause a dangerous spike in blood pressure.

S‑Amlodipine helps control blood pressure and chest pain (angina) by regulating how calcium moves into the muscle cells of the heart and blood vessels. Calcium is essential for muscle contraction, so limiting its entry keeps these muscles more relaxed.

• Calcium Channel Blockade: S‑Amlodipine belongs to the group of medicines called dihydropyridine calcium channel blockers. It specifically blocks L‑type calcium channels in the smooth muscle of blood vessels, preventing them from contracting too strongly.

• Widening of Blood Vessels (Peripheral Vasodilation): When the blood vessel muscles relax, the arteries widen. This lowers resistance in the circulation, making it easier for the heart to pump blood and helping reduce high blood pressure.

• Improved Heart Blood Flow (Coronary Dilation): S‑Amlodipine also relaxes the coronary arteries, which supply blood to the heart muscle. This improves oxygen delivery to the heart and helps prevent chest pain (angina) caused by reduced blood flow or spasms.

By lowering blood pressure, easing the workload on the heart, and improving blood supply to the heart muscle, S‑Amlodipine supports healthier cardiovascular function.

• Monitor for Swelling: If you experience swelling in the ankles or feet, try elevating your legs and reducing salt intake.

• Slow Transitions: To avoid dizziness, get up slowly from a sitting or lying position.

• Oral Health: Maintain good dental hygiene to prevent gum swelling, a rare side effect of calcium blockers.

• Grapefruit Juice: Do not consume grapefruit or its juice as it can significantly increase the drug's levels in your blood.

• FOOD (NO INTERACTION): Can be taken with or without food.

• Grapefruit Juice (MODERATE): Increases the concentration of S-Amlodipine, leading to an increased risk of side effects.

• Alcohol (CAUTION): May cause an excessive drop in blood pressure and increased drowsiness.

• Simvastatin (MODERATE): S-Amlodipine can increase levels of Simvastatin; dose limiting is usually required.

• CYP3A4 Inhibitors (MODERATE): Antifungals or certain antibiotics can increase the drug's effect.

• Tacrolimus (MODERATE): Blood levels of Tacrolimus may increase when taken with this medicine.

• Severe Aortic Stenosis (CAUTION): May increase the risk of heart failure due to reduced blood flow.

• Liver Disease (MODERATE): Requires careful monitoring due to slowed drug clearance.

• Heart Failure (CAUTION): Should be used with caution in patients with severe congestive heart failure.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose (within 12 hours), skip the missed one and continue your regular schedule. Do not take two doses at once to make up for a missed one.