What is Siglyn M 50/500 Tablet PR?

Siglyn M 50/500 Tablet PR is a combination of Sitagliptin and Metformin used to treat type 2 diabetes mellitus in adults. It improves blood glucose levels when combined with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while Sitagliptin increases insulin release. It is not for patients under 18.

When should Siglyn M 50/500 Tablet PR be avoided?

Siglyn M 50/500 Tablet PR should be avoided in patients with allergies to its components, severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.

Can Siglyn M 50/500 Tablet PR cause lactic acidosis?

Yes, Siglyn M 50/500 Tablet PR can lead to lactic acidosis, a rare but serious condition characterized by high lactic acid levels. Symptoms include muscle pain, dizziness, cold extremities, difficulty breathing, nausea, and slow heart rate. Seek immediate medical attention if these occur.

What are the side effects of Siglyn M 50/500 Tablet PR?

Common side effects of Siglyn M 50/500 Tablet PR include hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis and long-term use may lead to Vitamin B12 deficiency.

Can Siglyn M 50/500 Tablet PR cause Vitamin B12 deficiency?

Yes, long-term use of Siglyn M 50/500 Tablet PR can result in Vitamin B12 deficiency by interfering with its absorption, potentially leading to anemia and nerve issues. Annual Vitamin B12 supplementation is recommended to prevent these complications.

How should Siglyn M 50/500 Tablet PR be stored and disposed of?

Store Siglyn M 50/500 Tablet PR tightly closed in its original container, following the label instructions. Dispose of any unused medicine safely to prevent accidental ingestion by pets or children.

Is it safe to drink alcohol while taking Siglyn M 50/500 Tablet PR?

No, consuming alcohol with Siglyn M 50/500 Tablet PR is unsafe as it increases the risk of lactic acidosis.

PlatinumRx

Siglyn M 50/500mg Tablet PR 10s

Salt Composition:Metformin 500mg + Sitagliptin 50mg

Written by: Syed Jommy Abbas, B. Pharma

Reviewed by: Dr. Devika Rani, MBBS

Last updated on: 17-04-2025

Zydus Healthcare Ltd.

Strip of 10 tablets

Delivery by

...

FDA & GMP Certified

Long Expiry (>8 Months)

15 Days Easy Returns

General Information

Salt Composition

Metformin 500mg + Sitagliptin 50mg

Manufacturer

Zydus Healthcare Ltd.

Approved by

FDA

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Written by:

Syed Jommy Abbas

B. Pharma

Reviewed by:

Dr. Devika Rani

MBBS

Last updated on: 17-04-2025

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Manufacturer Address

Zydus Tower, CTS No- 460/6 of Village Pahadi, Off I. B. Patel Road, Goregaon (East), Mumbai-400 063

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