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Canagliflozin

Uses

Canagliflozin is used in the treatment of type 2 diabetes mellitus.

How it Works

How Canagliflozin Works Canagliflozin is an anti-diabetic medication. It functions by eliminating excess sugar from the body through urine.

Side Effects

Common side effects of Canagliflozin include urinary tract infection, increased thirst, nausea, constipation, genital fungal infection, polyuria, and rash.

Expert Advice

  • Canagliflozin is used alone or in combination with other diabetes medications to control blood sugar levels and prevent long-term complications.
  • It may lead to dehydration or increased urination. Ensure you drink plenty of water and stay hydrated.
  • Hypoglycemia (low blood sugar) may occur when used with other antidiabetic medications, alcohol, or if you delay or miss a meal.
  • Always carry sugary food or fruit juice in case you experience hypoglycemia symptoms, such as:
    • Cold sweats
    • Cool, pale skin
    • Tremors
    • Anxiety
  • Canagliflozin can cause genital fungal infections and/or urinary tract infections (UTIs) in both females and males; therefore, practice good hygiene.
  • Regularly monitor your blood sugar while taking this medication.
  • Inform your doctor immediately if you experience:
    • Constant dizziness
    • Joint pain
    • Cold-like symptoms
    • Unexplained nausea or vomiting
  • Canagliflozin also reduces the risk of heart attack, heart failure, and other cardiovascular events.
  • Continue to exercise regularly, maintain a healthy diet, and take your other prescribed diabetes medications alongside Canagliflozin.
  • It may contribute to weight loss and lower blood pressure.

Other Combinations

Canagliflozin + Metformin

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Frequently asked questions

Canagliflozin is used to lower blood sugar levels in adults with type 2 diabetes, particularly when combined with diet and exercise. It is also beneficial for adults with diabetes and cardiovascular disease, as it helps reduce the risk of heart attack, stroke, or death related to these conditions.
Canagliflozin may cause weight loss by reducing fat mass, though results can vary based on individual factors such as dosage and concurrent diabetes medications.
Canagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that lowers blood sugar by increasing glucose excretion in urine, while metformin is a biguanide that reduces liver sugar production.
Patients with a history of amputation, foot ulcers, heart disease, peripheral vascular disease, and neuropathy are at increased risk for lower limb amputation.
Monitor your blood sugar levels regularly and keep a record to discuss with your doctor, who will evaluate whether the medication is effective based on your results.
Take Canagliflozin as prescribed by your doctor, swallowing the tablet whole with water. It can be taken with or without food, but it's best to take it before your first meal of the day at the same time each day.
Serious side effects include ketoacidosis, allergic reactions, sudden kidney impairment, severe urinary tract infections, hypoglycemia, and a rare but serious bacterial infection in the perineum. It may also weaken bones, increasing fracture risk.
Canagliflozin may cause dehydration, vaginal yeast infections in women, skin yeast infections in men, and an increased risk of lower limb amputations in patients with a history of amputation or peripheral vascular disease.

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