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Entacapone

Uses

Entacapone is used in the treatment of Parkinson's disease.

How it Works

How Entacapone works Entacapone is a selective reversible inhibitor that is administered in combination with levodopa. It functions by inhibiting a chemical messenger known as catechol-O-methyl transferase (COMT), which helps increase the levels of dopamine in the body. An adequate amount of dopamine is essential for the brain to effectively coordinate body movements. This mechanism is how entacapone aids in the management of Parkinson's disease.

Side Effects

Common side effects of Entacapone include nausea, confusion, hallucinations, urine discoloration, insomnia (difficulty sleeping), diarrhea, ischemic heart disease, abdominal pain, and involuntary muscle movements.

Expert Advice

You have been prescribed Entacapone to enhance the effectiveness of levodopa for the treatment of Parkinson's disease.
This medication may cause significant drowsiness; avoid driving or engaging in activities that require concentration until you understand how it affects you.
To reduce the risk of dizziness or fainting, rise slowly from a sitting or lying position.
Inform your doctor if you experience impulsive behaviors, unusual actions, or an abnormally high sex drive.
Consult your doctor if you develop hallucinations or any other behavioral changes.
Diarrhea is a common side effect of this medication; therefore, ensure you drink plenty of fluids and monitor for any weight loss.
Do not be alarmed if you notice reddish-brown discoloration in your urine, as this is harmless.
Do not discontinue the medication abruptly without consulting your doctor.

Other Combinations

Carbidopa + Entacapone + Levodopa

Related Medications

Salt Composition in both

Levodopa 50mg + Carbidopa 12.5mg + Entacapone 200mg

Entacom Plus 50 Tablet

Intas Pharmaceuticals Ltd

Strip of 10 tablets

₹107.5

Syncapone 50/12.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹98.4

MRP ₹120

Salt Composition in both

Levodopa 50mg + Carbidopa 12.5mg + Entacapone 200mg

Elcapon 50 mg/12.5 mg/200 mg Tablet

Strip of 10 tablets

₹53.6

Syncapone 50/12.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹98.4

MRP ₹120

Salt Composition in both

Levodopa 50mg + Carbidopa 12.5mg + Entacapone 200mg

Tidomet E 50mg/12.5mg/200mg Tablet

Torrent Pharmaceuticals Ltd

Strip of 10 tablets

₹48.3

Syncapone 50/12.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹98.4

MRP ₹120

Salt Composition in both

Levodopa 50mg + Carbidopa 12.5mg + Entacapone 200mg

Elcepan 50mg/12.5mg/200mg Tablet

Strip of 10 tablets

₹53

Syncapone 50/12.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹98.4

MRP ₹120

Salt Composition

Carbidopa 12.5mg + Entacapone 200mg + Levodopa 50mg

Syncapone 50/12.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹98.4

MRP ₹120

Salt Composition in both

Levodopa 100mg + Carbidopa 25mg + Entacapone 200mg

Tidomet E 100mg/25mg/200mg Tablet

Torrent Pharmaceuticals Ltd

Strip of 10 tablets

₹55.4

Entacom Plus 100mg Tablet 10s

Intas Pharmaceuticals Ltd.

Strip of 10 tablets

₹125.3

MRP ₹151

Salt Composition in both

Levodopa 100mg + Carbidopa 25mg + Entacapone 200mg

Elcapon 100 mg/25 mg/200 mg Tablet

Strip of 10 tablets

₹61.5

Entacom Plus 100mg Tablet 10s

Intas Pharmaceuticals Ltd.

Strip of 10 tablets

₹125.3

MRP ₹151

Salt Composition in both

Levodopa 100mg + Carbidopa 25mg + Entacapone 200mg

Elcepan 100mg/25mg/200mg Tablet

Strip of 10 tablets

₹61

Entacom Plus 100mg Tablet 10s

Intas Pharmaceuticals Ltd.

Strip of 10 tablets

₹125.3

MRP ₹151

Salt Composition

Carbidopa 25mg + Entacapone 200mg + Levodopa 100mg

Entacom Plus 100mg Tablet 10s

Intas Pharmaceuticals Ltd.

Strip of 10 tablets

₹125.3

MRP ₹151

Salt Composition in both

Entacapone 200mg

Entacom 200mg Tablet 10s

Intas Pharmaceuticals Ltd.

Strip of 10 tablets

₹92.3

Adcapone 200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹86.1

MRP ₹105

Salt Composition

Entacapone 200mg

Adcapone 200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹86.1

MRP ₹105

Salt Composition in both

Levodopa 150mg + Carbidopa 37.5mg + Entacapone 200mg

Tidomet E 150mg/37.5mg/200mg Tablet

Torrent Pharmaceuticals Ltd

Strip of 10 tablets

₹63

Syncapone 150/37.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹121.4

MRP ₹148

Salt Composition

Carbidopa 37.5mg + Entacapone 200mg + Levodopa 150mg

Syncapone 150/37.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹121.4

MRP ₹148

Salt Composition in both

Levodopa 150mg + Carbidopa 37.5mg + Entacapone 200mg

Entacom Plus 150 Tablet

Intas Pharmaceuticals Ltd

Strip of 10 tablets

₹143

Syncapone 150/37.5/200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹121.4

MRP ₹148

Salt Composition in both

Carbidopa 25mg + Entacapone 200mg + Levodopa 100mg

Syncapone 100 25/200/100mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

Strip of 10 tablets

₹140

Entacom Plus 100mg Tablet 10s

Intas Pharmaceuticals Ltd.

Strip of 10 tablets

₹125.3

MRP ₹151

Frequently asked questions

Can Entacapone cause sleepiness?

Yes, the combination of Entacapone and levodopa may lead to excessive daytime sleepiness and sudden sleep onset. Consult your doctor if these symptoms occur.

Does Entacapone affect fertility?

No, Entacapone does not affect fertility, but it should be avoided by pregnant or lactating women due to insufficient safety data.

Is Entacapone a dopamine agonist?

No, Entacapone is not a dopamine agonist; it is a selective and reversible COMT inhibitor that enhances and sustains levodopa levels.

What class of drug is Entacapone?

Entacapone is classified as a COMT (catechol-O-methyltransferase) inhibitor.

Does Entacapone affect urine color?

Yes, Entacapone may cause urine to turn brownish-orange, which is a common and harmless effect.

When is the best time to take Entacapone?

Entacapone can be taken at any time but should ideally be taken around the same time each day for better adherence.

Does Entacapone cross the blood-brain barrier?

No, Entacapone does not cross the blood-brain barrier but helps prolong the benefits of levodopa doses.

What is impulse control disorder related to Entacapone?

Impulse control disorders involve urges to engage in unusual behaviors, such as compulsive gambling or excessive spending. If experienced, consult your doctor for possible dose adjustments.

Can Entacapone be crushed or split, and how should it be taken?

No, Entacapone should not be crushed or split. It should be taken whole with a full glass of water at the same time as a dose of levodopa.

What should I do if I take more than the recommended dose of Entacapone?

If you accidentally take more than the recommended dose, you may experience confusion, sleepiness, and other symptoms. Seek immediate medical attention.

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