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Entecavir

Uses

Entecavir is used in the treatment of chronic hepatitis B virus (HBV) infection.

How it Works

How Entecavir works: Entecavir is an antiviral medication that inhibits the replication of the virus in human cells. This action prevents the virus from producing new viral particles and helps to resolve the infection.

Side Effects

Common side effects of Entecavir include increased alanine aminotransferase levels.

Expert Advice

You have been prescribed Entecavir for the treatment of chronic hepatitis B virus (HBV) infection.
Take it on an empty stomach, at least 2 hours after or before a meal.
Entecavir may cause dizziness or sleepiness.
Do not drive or engage in activities requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infections while taking this medication.
You can also transmit HIV or HBV to others.
Do not share needles or personal items that may have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are required to monitor:

Liver function
Level of hepatitis B virus
Blood cell counts

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Frequently asked questions

How should Entecavir be taken?

Entecavir should be taken exactly as prescribed by your doctor, usually once daily on an empty stomach, at least 2 hours after a meal and 2 hours before the next meal. Aim to take it at the same time each day. Consult your doctor if you have any questions.

Can Entecavir cure hepatitis B?

No, Entecavir does not cure hepatitis B but may improve liver condition by reducing the amount of hepatitis B virus (HBV) in the body, limiting its ability to replicate and infect new liver cells.

How long should I take Entecavir?

Do not discontinue Entecavir without consulting your doctor, as stopping treatment prematurely may worsen your hepatitis, especially in the first few months after cessation. Adhere strictly to the prescribed dosage.

Can Entecavir cause liver problems?

Yes, Entecavir can lead to serious liver issues such as hepatomegaly (enlargement of the liver) and steatosis (fat buildup in the liver). This combination is a medical emergency requiring immediate attention.

What are the symptoms of serious liver problems?

Symptoms of liver problems include jaundice (yellowing of the skin or eyes), dark urine, light-colored stools, loss of appetite, nausea, and stomach pain. These symptoms are more prevalent in women, overweight individuals, or those on Entecavir for extended periods. Contact your doctor immediately if you experience any of these symptoms.

What is drug resistance? Can I develop drug resistance with Entecavir?

Drug resistance occurs when a medication that was once effective becomes ineffective due to changes in the virus or bacteria. With Entecavir, resistance is more likely if you take a lower dose than recommended.

What if HIV infection co-exists with HBV infection? Will this affect treatment with Entecavir?

Entecavir is not recommended for HBV patients with co-existing HIV unless they are receiving HIV treatment. Starting Entecavir in these patients may lead to resistance against HIV medications. Testing for HIV is advised before initiating Entecavir treatment.

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