Epalrestat + Pregabalin
Uses
Epalrestat and Pregabalin are used in the treatment of neuropathic pain.
How it Works
How Epalrestat and Pregabalin work Epalrestat and Pregabalin is a combination of two medicines that treat neuropathic pain. Epalrestat is an aldose reductase inhibitor that blocks the accumulation of sorbitol in cells, which contributes to diabetic nerve disease. Pregabalin is an alpha 2 delta ligand that decreases pain by modulating the calcium channel activity of nerve cells.
Side Effects
Common side effects of Epalrestat and Pregabalin include nausea, vomiting, diarrhea, drowsiness, dizziness, uncoordinated body movements, and increased liver enzymes.
Expert Advice
- Take the medication only as per the dose and duration prescribed by your doctor.
- Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
- Inform your doctor if you experience:
- Cut or sore on your feet that is infectious or not healing
- Burning or tingling sensation in arms or feet that hampers your routine activities
- Trouble with digestion, urination, or sexual functioning
- Dizziness
- To prevent diabetic nerve pain:
- Wear proper footwear
- Examine your feet every day to detect lesions early
- Monitor your blood sugar levels regularly.
- Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding.
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