Profile
Search

Isoniazid + Rifampicin

Uses

Rifampicin and Isoniazid are used in the treatment of tuberculosis.

How it Works

How Rifampicin and Isoniazid Work Rifampicin and Isoniazid are a combination of two antibiotics that treat tuberculosis (TB). Rifampicin inactivates a bacterial enzyme, RNA polymerase, which is essential for TB bacteria to produce vital proteins and reproduce. Isoniazid prevents these bacteria from forming their protective covering. Together, they kill the bacteria and eradicate the infection.

Side Effects

Common side effects of Rifampicin and Isoniazid include vomiting, nausea, peripheral neuropathy (tingling and numbness in the hands and feet), abdominal pain, skin rash, itching, hepatitis (viral infection of the liver), dizziness, lethargy, and low blood platelets.

Expert Advice

  • You have been prescribed Rifampicin + Isoniazid for the treatment of tuberculosis.
  • Complete the full course of the medication, even if you feel better. Stopping it early may cause the infection to return.
  • Take the medication on an empty stomach, preferably at the same time every day.
  • It may cause discolouration of your urine, sweat, saliva, and tears to a reddish-orange color. This is normal and not harmful.
  • Your doctor may check your liver function before starting treatment and regularly thereafter.
  • Inform your doctor if you notice any of the following symptoms:
    • Yellowing of the eyes or skin
    • Dark urine
    • Stomach pain
  • Avoid drinking alcohol while taking Rifampicin + Isoniazid, as this may increase the risk of liver side effects.
  • Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while taking Rifampicin + Isoniazid, as it may reduce the effectiveness of hormonal contraceptives like the pill.
  • Do not take indigestion remedies (antacids) within at least two hours of taking Rifampicin + Isoniazid.

Related Medications

Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Recox 450mg/300mg Tablet
Jarson Pharmaceuticals
Strip of 10 tablets
MRP

54.4

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Rifalin I 450 mg/300 mg Tablet
Lincoln Pharmaceuticals Ltd
Strip of 10 tablets
MRP

52.5

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Rifanex 450mg/300mg Tablet
PCI Pharmaceuticals
Strip of 10 tablets
MRP

39.6

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 100mg + Isoniazid 50mg

hero_image
Binex 100mg/50mg Tablet DT
Biological E Ltd
Strip of 10 tablets
MRP

13.3

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 225mg + Isoniazid 150mg

hero_image
Wokex 4FD 225 mg/150 mg Tablet
Wockhardt Ltd
Strip of 4 tablets
MRP

19.7

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Rizide 450 mg/300 mg Tablet
Prayas Pharmaceuticals
Bottle of 100 tablets
MRP

7.3

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Tibikit Plus 450 mg/300 mg Tablet
Sun Pharmaceutical Industries Ltd
Strip of 1 tablets
MRP

19.7

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
ANACOX-PLUS 450MG/300MG TABLET
Ajanta Pharma Ltd
Strip of 4 tablets
MRP

26

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin NA + Isoniazid NA

hero_image
Akurit LD Tablet
Lupin Ltd
Strip of 6 tablets
MRP

13

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 125mg + Isoniazid NA

hero_image
Lynacox Tablet DT
Lancer Health Care Pvt Ltd
Strip of 10 tablets
MRP

11.2

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Coxter 450 mg/300 mg Tablet
Alkem Laboratories Ltd
Strip of 10 tablets
MRP

52.4

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 150mg + Isoniazid 75mg

hero_image
Rimmax 2Fdc 150 mg/75 mg Tablet
Novartis India Ltd
Strip of 6 tablets
MRP

11.7

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 225mg

hero_image
Scc 2 450 mg/225 mg Powder
Maneesh Pharmaceuticals Ltd
Box of 1 powders
MRP

16.5

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Eufacin Inh 450 mg/300 mg Tablet
Euphoric Pharmaceuticals Pvt Ltd
Strip of 10 tablets
MRP

44.4

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Zucox Plus 450 mg/300 mg Tablet
Glaxo SmithKline Pharmaceuticals Ltd
Strip of 10 tablets
MRP

62.4

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 200mg + Isoniazid 150mg

hero_image
Vicox Kid Forte 200 mg/150 mg Tablet
Shrinivas Gujarat Laboratories Pvt Ltd
Strip of 10 tablets
MRP

38

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Parkox 450mg/300mg Tablet
Park Pharmaceuticals
Strip of 10 tablets
MRP

69.5

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 60mg + Isoniazid 30mg

hero_image
Tbrid Kid 60mg/30mg Tablet
Bonsai Pharma
Strip of 10 tablets
MRP

12.6

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Rikox 450mg/300mg Tablet
Aan Pharma Pvt Ltd
Strip of 10 tablets
MRP

68

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
RIFAKEM-INH 450MG/300MG CAPSULE
Alkem Laboratories Ltd
Strip of 10 capsules
MRP

67.7

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
TRICINEX 450MG/300MG CAPSULE
Zee Laboratories
Strip of 10 capsules
MRP

58

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Coxyzide 450mg/300mg Capsule
Pharmasynth Formulations Ltd
Strip of 10 capsules
MRP

42

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 100mg + Isoniazid 50mg

hero_image
Rimactazid 100 mg/50 mg Tablet DT
Novartis India Ltd
Strip of 10 tablets
MRP

12.2

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 225mg + Isoniazid 150mg

hero_image
Caviter FD Tablet 225mg/150mg
Wockhardt Ltd
Strip of 4 tablets
MRP

19.9

No Substitute
Sorry, Substitute Medicine is Unavailable
Molecule
Salt Composition

Rifampicin 450mg + Isoniazid 300mg

hero_image
Rifarcin Plus 450 mg/300 mg Tablet
Reliance Formulation Pvt Ltd
Strip of 10 tablets
MRP

56.2

No Substitute
Sorry, Substitute Medicine is Unavailable

Frequently asked questions

Rifampicin+Isoniazid is a combination medication used to treat tuberculosis. Rifampicin inhibits bacterial RNA-polymerase, essential for bacterial protein synthesis and reproduction, while Isoniazid prevents the bacteria from forming a protective covering. Together, they effectively kill the bacteria and eliminate the infection.
Yes, Rifampicin+Isoniazid can cause urine, skin, sweat, saliva, tears, and feces to turn brownish-red or orange. This change is harmless.
Take Rifampicin+Isoniazid as directed by your doctor, preferably on an empty stomach—one hour before or two hours after meals.
Store the medication in its original container, tightly closed, following the storage instructions on the label. Dispose of any unused medicine properly to prevent accidental ingestion by pets, children, or others.
Yes, Rifampicin+Isoniazid can reduce the effectiveness of birth control pills. Consult your doctor about alternative contraceptive methods that do not affect hormone levels, such as condoms or diaphragms.
Complete the full course of the prescribed medication, even if you feel better. Avoid alcohol during treatment to reduce the risk of liver damage. Contact your doctor immediately if you experience vision changes, loss of appetite, fatigue, stomach pain, nausea, vomiting, yellowing of the skin or eyes, or dark urine.

Flat ₹100 off on first app order   |    Use Code:  APP100   | 

Flat ₹100 off on first app order

USE CODE: APP100

PlatinumCare

Download Now

AppleIconPlayStoreIcon