Palbociclib

Uses

Palbociclib Uses Palbociclib is used in the treatment of breast cancer. It is also used to treat patients with specific types of breast cancer, including estrogen receptor-positive and human epidermal growth factor receptor 2-negative, that have spread to other organs. It is administered in conjunction with hormonal anticancer therapies.

How it Works

How Palbociclib works Palbociclib is an anti-cancer medication. Cyclin-dependent kinases 4 and 6, which are chemical messengers, are downstream of signaling pathways that lead to cell proliferation. This medication works by inhibiting cyclin-dependent kinases 4 and 6, thereby arresting the cancer cell cycle. Additionally, it targets estrogen receptor-positive breast cancer cells by disrupting the cell cycle.

Side Effects

Common side effects of Palbociclib include fatigue, hair loss, rash, vomiting, diarrhea, nausea, decreased appetite, infection, stomatitis (inflammation of the mouth), anemia (low red blood cell count), weakness, fever, and decreased white blood cell count.

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