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Probenecid

Uses

Probenecid is used in the treatment of gout.

How it Works

How Probenecid Works Probenecid is a urine alkalizer. It functions by increasing the pH of urine, making it less acidic. This process aids the kidneys in eliminating excess uric acid, thereby preventing gout and certain types of kidney stones.

Side Effects

Common side effects of Probenecid include nausea, vomiting, headache, gout flares, fever, rash, aplastic anemia, hemolytic anemia, and decreased white blood cell count (lymphocytes).

Expert Advice

Do not use probenecid along with salicylates, such as aspirin.
You may be prescribed colchicine or a non-steroidal anti-inflammatory agent (NSAID, pain killer) to prevent severe gouty attacks during the first 6 to 12 months of probenecid therapy.
Consult your doctor before starting probenecid treatment if you have or have ever had:
- Kidney stones
- Any other kidney disorder
- Ulcers in the stomach and small intestine (peptic ulcers)
- Diabetes
- Severe liver disorders
- Blood disorders
- Glucose 6-phosphate dehydrogenase (G6PD) deficiency
Inform your doctor about any scheduled surgery for which you will be receiving anesthetics.
You should consume adequate water or fluids while taking probenecid to prevent kidney stones.
Notify your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
Take precautions while driving or operating machinery, as probenecid is known to cause dizziness.

Other Combinations

Amoxycillin + Cloxacillin + Probenecid

Amoxycillin + Probenecid

Ampicillin + Probenecid

Cefadroxil + Probenecid

Cefalexin + Probenecid

Related Medications

Salt Composition

Probenecid 500mg

Bencid 500mg Tablet 10s

Geno Pharmaceuticals Ltd.

Strip of 10 tablets

₹74.8

Sorry, Substitute Medicine is Unavailable

Salt Composition

Ampicillin 250mg + Probenecid 250mg

Prompicin 250mg/250mg Capsule

Geno Pharmaceuticals Ltd

Strip of 10 capsules

₹36.8

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 250mg + Probenecid 250mg

Unifex 250 mg/250 mg Tablet

BestoChem Formulations India Ltd

Strip of 10 tablets

₹76.2

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefadroxil NA + Probenecid NA

Distaclor PD Drop

Pharma Link Pvt Ltd

Packet of 10 ml

₹92

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin NA + Probenecid NA

Procef Forte Tablet

Alpha Pharmaceuticals

Strip of 10 tablets

₹148.5

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 500mg + Probenecid 500mg

Phexibid Forte 500mg/500mg Tablet

Cyper Drugs & Pharmaceuticals Pvt Ltd

Strip of 10 tablets

₹110

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefadroxil 250mg + Probenecid 250mg

Dax LA 250 mg/250 mg Tablet

DWD Pharmaceuticals Ltd

Strip of 6 tablets

₹13.9

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 500mg + Probenecid 500mg

Ceff LA 500mg/500mg Tablet

Strip of 10 tablets

₹185.6

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 250mg + Probenecid 250mg

Alcephin LA 250 mg/250 mg Tablet

Alembic Pharmaceuticals Ltd

Strip of 10 tablets

₹66.7

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefadroxil 500mg + Probenecid 500mg

Dax LA 500 mg/500 mg Tablet

DWD Pharmaceuticals Ltd

Strip of 6 tablets

₹26.7

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 250mg + Probenecid 250mg

Phexibid 250mg/250mg Tablet

Cyper Drugs & Pharmaceuticals Pvt Ltd

Strip of 10 tablets

₹65

Sorry, Substitute Medicine is Unavailable

Salt Composition

Ampicillin 250mg + Probenecid 250mg

Ampilong 250 mg/250 mg Tablet

Dr Reddy's Laboratories Ltd

Strip of 10 tablets

₹37.2

Sorry, Substitute Medicine is Unavailable

Salt Composition

Ampicillin 750mg + Probenecid NA

Algen Healthcare Limited

Strip of 10 tablets

₹89

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 500mg + Probenecid 500mg

Procef Forte 500mg/500mg Tablet

Alpha Drugs & Pharmaceuticals

Strip of 10 tablets

₹120

Sorry, Substitute Medicine is Unavailable

Salt Composition

Ampicillin NA + Probenecid NA

Mech Pharmaceuticals

Strip of 10 tablets

₹50.3

Sorry, Substitute Medicine is Unavailable

Salt Composition

Amoxycillin 500mg + Probenecid 500mg

Moxylong DS 500 mg/500 mg Tablet

Dr Reddy's Laboratories Ltd

Strip of 10 tablets

₹75.4

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefadroxil 500mg + Probenecid 500mg

Mydrox 500mg/500mg Tablet

Solitaire Pharmacia Pvt Ltd

Strip of 10 tablets

₹46.5

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 250mg + Probenecid 250mg

Ceff LA 250mg/250mg Tablet

Strip of 10 tablets

₹92

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 500mg + Probenecid 250mg

Unifex Forte 500mg/250mg Tablet

BestoChem Formulations India Ltd

Strip of 10 tablets

₹215

Sorry, Substitute Medicine is Unavailable

Salt Composition

Ampicillin 500mg + Probenecid 500mg

Ampilong DS 500 mg/500 mg Tablet

Dr Reddy's Laboratories Ltd

Strip of 10 tablets

₹71.8

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 500mg + Probenecid 500mg

Unifex 500 mg/500 mg Capsule

BestoChem Formulations India Ltd

Strip of 10 capsules

₹95.9

Sorry, Substitute Medicine is Unavailable

Salt Composition

Amoxycillin 250mg + Probenecid 250mg

Moxylong SS 250 mg/250 mg Tablet

Dr Reddy's Laboratories Ltd

Strip of 10 tablets

₹40.3

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefadroxil 500mg + Probenecid 500mg

Nocid OM 500mg/500mg Capsule

Rubra Pharmaceuticals Ltd

Strip of 10 capsules

₹45

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 500mg + Probenecid 500mg

Cefalong DS 500mg/500mg Capsule

Dr Reddy's Laboratories Ltd

Strip of 10 capsules

₹134.2

Sorry, Substitute Medicine is Unavailable

Salt Composition

Cefalexin 500mg + Probenecid 500mg

Alcephin LA 500 mg/500 mg Tablet

Alembic Pharmaceuticals Ltd

Strip of 10 tablets

₹112.7

Sorry, Substitute Medicine is Unavailable

Frequently asked questions

What is probenecid used for?

Probenecid is a uricosuric agent used to lower uric acid levels and to prevent and treat gout and gouty arthritis. It is also used to enhance the effectiveness of antibiotics like penicillin.

Does probenecid cause kidney stones?

Yes, kidney stones are a known side effect of probenecid treatment.

Why is probenecid given with penicillin?

Probenecid is prescribed with penicillin in certain serious infections to prolong the antibiotic's effect. It works by inhibiting the kidney's elimination of penicillin, increasing its concentration in the blood.

Is probenecid an NSAID, antibiotic, sulfa drug, or diuretic?

No, probenecid is a uricosuric agent used to lower uric acid levels and treat gout. It does not have anti-inflammatory properties like NSAIDs, nor does it fight infections like antibiotics or sulfa drugs. It is sometimes used with antibiotics to enhance their effect but is not a diuretic.

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