Sirolimus

Uses

Sirolimus is used for the prevention of kidney transplant rejection.

How it Works

How Sirolimus works Sirolimus is an immunosuppressant that functions by suppressing the body’s immune response after the transplantation of an organ (e.g., liver, kidney, heart). This mechanism helps the body accept the new organ as if it were its own.

Side Effects

Common side effects of Sirolimus include decreased white blood cell count (neutrophils), stomatitis (inflammation of the mouth), sepsis, kidney infection, cytomegalovirus infection, herpes zoster, non-melanoma skin cancer, hemolytic uremic syndrome, hypersensitivity, pericardial effusion, venous thrombosis, pulmonary embolism, pneumonitis, pleural effusion, nosebleeds, pancreatic inflammation, ascites (accumulation of fluid in the abdominal cavity), osteonecrosis (reduced blood flow to the bones), and ovarian cysts.

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