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Citidolin P 500mg/400mg Tablet

Citidolin P 500mg/400mg Tablet is a combination neuroprotective medicine used to support brain function in conditions involving memory loss, impaired cognition, stroke recovery, and age-related decline in mental performance. It contains Citicoline and Piracetam, two agents that enhance neuronal repair, improve blood flow to the brain, and boost communication between nerve cells. The tablet is used to improve alertness, attention, concentration, and overall brain vitality in individuals with chronic neurological illnesses.

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Written by: Syed Jommy Abbas, B. Pharma

Reviewed by: Dr. Devika Rani, MBBS

Last updated on: 19-05-2026

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Citidolin P 500mg/400mg Tablet
Citidolin P 500mg/400mg Tablet
Citidolin P 500mg/400mg Tablet

Mediyork Pharma Pvt. Ltd.

Strip of 10 tablets
MRP468.8
46.9 / Unit

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Detailed Description

Citidolin P 500mg/400mg Tablet is a prescription nootropic formulation designed to improve cognitive performance and support the recovery of brain cells after injury. Each tablet contains a scientifically validated combination of Citicoline and Piracetam, two agents with complementary mechanisms that target neuronal metabolism, neurotransmitter balance, membrane repair, and microcirculation within the brain.

Citicoline is a naturally occurring compound that serves as a source of choline and cytidine, essential for synthesising phospholipids that rebuild damaged neuronal membranes. By stabilising brain cell structures and promoting neurotransmitters such as dopamine, noradrenaline, and acetylcholine, Citicoline enhances learning ability, memory processing, and attention span. It also reduces brain swelling, protects cells from free radical damage, and boosts energy utilisation in nerve tissues.

Piracetam, a well-studied nootropic, improves neuronal function by enhancing the fluidity of cell membranes and facilitating communication between brain cells. It increases oxygen uptake, glucose utilisation, and neurotransmitter release, all of which collectively improve mental clarity and cognitive performance. Piracetam also modulates platelet aggregation and microcirculation, improving blood flow to regions of the brain that need nourishment.

Together, Citicoline and Piracetam work in synergy to improve brain metabolism, support neuroplasticity, and promote recovery after stroke, head injury, or age-related cognitive decline. Neurologists frequently prescribe Strocit Plus Tablet for individuals experiencing memory issues, difficulty concentrating, vertigo, behavioural changes, and slowed thought processing. The dual action of this combination helps restore sharpness, stabilise mood, and reduce the progression of neurological deterioration.

This medicine must be taken only under the guidance of a doctor, especially in elderly individuals or patients with kidney problems, bleeding disorders, or a history of seizures. When used consistently and alongside rehabilitative therapies such as physiotherapy, occupational therapy, and cognitive training, Citidolin P 500mg/400mg Tablet can significantly enhance neurological outcomes and daily functioning.

Uses of Citidolin P 500mg/400mg Tablet

Citidolin P 500mg/400mg Tablet Tablet is prescribed for a wide range of neurological and cognitive disorders in which memory, behaviour, attention, or brain recovery is affected. Its dual-action formulation Citicoline + Piracetam supports neuronal repair, enhances blood flow to critical brain areas, and improves communication between nerve cells. Key therapeutic uses include:

1. Post-Stroke Recovery

Citidolin P 500mg/400mg Tablet is commonly used as part of stroke rehabilitation. It helps by:

1. Supporting neuronal repair and membrane restructuring, which aids in recovery after ischaemic or haemorrhagic stroke.

2. Improving coordination, motor function, and cognitive deficits during the recovery period.

3. Restoring attention, speech, memory, and processing speed, which often decline after a cerebrovascular event.

This combination is routinely prescribed alongside physiotherapy, speech therapy, and occupational rehabilitation.

2. Cognitive Impairment & Dementia

Citidolin P 500mg/400mg Tablet provides clinically beneficial support in several forms of cognitive decline, such as:

1. Mild Cognitive Impairment (MCI)

2. Alzheimer's-type dementia

3. Age-related memory deterioration

The medicine enhances neurotransmission, boosts acetylcholine levels, improves brain metabolism, and helps slow functional decline, thereby improving day-to-day cognition and quality of life.

3. Traumatic Brain Injury (TBI)

After a head injury, many individuals experience confusion, irritability, slowed thinking, and memory gaps. Strocit Plus helps by:

1. Enhancing the brain's natural healing mechanisms

2. Reducing post-injury cognitive disturbances

3. Improving attention, mental clarity, response time, and problem-solving

Its neuroprotective effect makes it worthwhile in both mild and moderate TBI, including concussion-related cognitive issues.

4. Behavioural and Cognitive Changes in the Elderly

Behavioural fluctuations and reduced mental initiative often accompany ageing. Citidolin P 500mg/400mg Tablet may help address:

1. Low motivation and lack of initiative

2. Poor attention span or difficulty concentrating

3. Irritability or agitation

4. Slowed thought processes

5. Fluctuations in mood and emotional stability

Consistent use helps maintain mental sharpness and improves social and cognitive functioning.

5. Learning Difficulties & Attention-Related Issues

Although not a primary learning-disorder medicine, neurologists may prescribe Citidolin P 500mg/400mg Tablet for individuals who experience:

1. Reduced alertness

2. Difficulty processing information

3. Slow comprehension

4. Fatigue-related cognitive decline

By improving neurotransmission and cerebral energy utilisation, it can enhance mental performance in select cases under medical supervision.

6. Vertigo and Balance Disorders

Piracetam, one of the components of [MEDICINE_NAME], is known to:

1. Increase inner-ear microcirculation

2. Reduce abnormal sensory signals that contribute to vertigo

3. Improve stability and balance in certain vestibular disorders

It is often used when vertigo is associated with compromised cerebral or cochlear blood flow.

7. Post-Surgical Neurological Weakness

In individuals recovering from neurosurgical procedures or prolonged ICU stays, Citidolin P 500mg/400mg Tablet helps by:

1. Supporting brain-cell regeneration

2. Enhancing cognitive recovery

3. Improving concentration and mental alertness

4. Reducing confusion or post-operative cognitive dysfunction

It is often included in comprehensive rehabilitation plans.

Benefits of Citidolin P 500mg/400mg Tablet

Citidolin P 500mg/400mg Tablet offers multiple cognitive and neuroprotective benefits due to the synergistic actions of Citicoline and Piracetam. Its broad spectrum of advantages includes:

1. Enhances Memory, Recall, and Learning Ability

1. Citicoline boosts phospholipid synthesis, which is vital for forming new memory circuits.

2. Piracetam enhances neurotransmitter release and synaptic communication, helping improve the speed and efficiency with which the brain stores and retrieves information.

These effects make the medicine helpful for both age-related and injury-related memory disturbances.

2. Promotes Brain Cell Repair and Regeneration

Citidolin P 500mg/400mg Tablet actively supports:

1. Repair of damaged neuronal membranes

2. Restoration of neurotransmitter balance

3. Improved structural integrity of brain cells after stroke, trauma, or oxygen deprivation

This regenerative capability is one of the key reasons it is widely used in stroke and TBI recovery.

3. Boosts Attention, Focus, and Alertness

By improving oxygen utilisation, glucose metabolism, and synaptic activity, the formulation helps:

1. Increase mental clarity

2. Improve sustained attention

3. Reduce cognitive fatigue

4. Enhance overall alertness

This benefit is especially valuable in elderly patients or individuals recovering from neurological insults.

4. Protects Brain Cells from Ongoing Damage

The combination functions as a potent neuroprotective agent, shielding neurons from:

1. Oxidative stress and free-radical injury

2. Inflammatory processes linked to chronic neurological disorders

3. Ischaemia, which reduces oxygen supply to vulnerable brain regions

These protective actions help slow the progression of cognitive decline.

5. Increases Cognitive Speed and Processing Efficiency

Citidolin P 500mg/400mg Tablet enhances the brain's ability to:

1. Analyse information quickly

2. Respond efficiently to tasks

3. Maintain sharper cognitive performance

4. Handle complex mental activities with greater ease

This improvement in mental processing can positively impact daily activities, work performance, and rehabilitative outcomes.

6. Improves Microcirculation and Brain Blood Flow

Piracetam is known to:

1. Reduce platelet aggregation

2. Improve the deformability of red blood cells

3. Enhance cerebral microcirculation

This is especially useful in stroke survivors, elderly patients, and individuals with chronic small-vessel disease.

7. Reduces Long-Term Disability after Stroke

Regular use of Citidolin P 500mg/400mg Tablet as part of post-stroke care can:

1. Improve cognitive and motor recovery

2. Restore independence in daily tasks

3. Prevent worsening of neurological deficits

4. Support better outcomes in physiotherapy and speech therapy

This contributes to a more comprehensive and sustainable rehabilitation process.

8. Stabilises Mood and Improves Behavioural Symptoms

Citicoline helps regulate neurotransmitter levels such as dopamine and acetylcholine, while Piracetam improves neuronal communication. Together, they help:

1. Stabilise mood swings

2. Improve emotional balance

3. Reduce irritability

4. Enhance motivation and initiative

5. Support better social interaction and behavioural control

These benefits are particularly relevant in elderly patients or those with stroke-related behavioural changes.

Side Effects of Citidolin P 500mg/400mg Tablet

Side Effects of Citidolin P 500mg/400mg Tablet

Citidolin P 500mg/400mg Tablet is generally well tolerated. However, some individuals may experience mild, transient symptoms such as:

1. Headache

2. Nausea

3. Vomiting

4. Nervousness or restlessness

5. Insomnia

6. Increased heart rate

7. Sweating

8. Tremors

9. Stomach discomfort

10. Diarrhoea

11. Weight gain (rare)

12. Irritability

13. Rash (very rare)

Directions for Use

How to Use Citidolin P 500mg/400mg Tablet

1. Take the tablet exactly as prescribed.

2. Usually taken 1–2 times daily, preferably after meals.

3. Swallow whole with a glass of water.

4. Do not crush or break unless advised.

5. Continue treatment for the duration recommended by your physician; neurological medicines require consistency.

How it works

How Citidolin P 500mg/400mg Tablet Works

1. Citicoline

1. Increases synthesis of phosphatidylcholine—essential for neuronal membrane repair.

2. Boosts acetylcholine production, enhancing memory, alertness, and learning.

3. Protects neurons from oxidative stress.

4. Improves cerebral blood flow and reduces swelling.

5. Enhances mitochondrial energy production in brain cells.

2. Piracetam

1. Improves neuronal membrane fluidity, helping brain cells communicate more efficiently.

2. Enhances neurotransmission of glutamate, acetylcholine, and dopamine.

3. Increases oxygen utilisation and glucose uptake in the brain.

4. Improves microcirculation by reducing platelet aggregation.

5. Strengthens cognitive processing and alertness.

Synergistic Effect

Together, Citicoline and Piracetam:

1. Restore damaged neural pathways

2. Promote neuroplasticity

3. Improve memory circuits

4. Support long-term cognitive stability

Safety Advice for Citidolin P 500mg/400mg Tablet

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Breastfeeding
Caution

Avoid applying ointments to the chest area where the infant may come into direct contact or swallow it.

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Driving
Safe

This medicine does not cause drowsiness and is safe for drivers.

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Kidney
Safe

External and inhalant use does not significantly involve liver or kidney metabolism.

icon
Alcohol
Safe

There are no known interactions with alcohol for this inhalant.

icon
Children
Caution

Do not use in children under 2 years of age. In older children, ensure they are supervised to prevent accidental ingestion.

icon
Pregnancy
Safe

No known risks associated with topical use during pregnancy, though consulting a doctor is always advised.

icon
Breastfeeding
Caution

Avoid applying ointments to the chest area where the infant may come into direct contact or swallow it.

icon
Driving
Safe

This medicine does not cause drowsiness and is safe for drivers.

icon
Kidney
Safe

External and inhalant use does not significantly involve liver or kidney metabolism.

icon
Alcohol
Safe

There are no known interactions with alcohol for this inhalant.

icon
Children
Caution

Do not use in children under 2 years of age. In older children, ensure they are supervised to prevent accidental ingestion.

icon
Pregnancy
Safe

No known risks associated with topical use during pregnancy, though consulting a doctor is always advised.

Quick Tips for Citidolin P 500mg/400mg Tablet

Quick Tips for Citidolin P 500mg/400mg Tablet

1. Take Citidolin P 500mg/400mg Tablet at the same time every day to maintain steady levels.

2. Continue medication even if you feel better—neurological recovery takes time.

3. Combine with physiotherapy, cognitive exercises, memory training, and a nutritious diet for the best results.

4. Avoid alcohol and smoking for optimal brain recovery.

5. Report unusual bleeding, severe irritability, or confusion.

Storage Advice

1. Store in a cool, dry place below 25°C.

2. Protect from moisture and direct sunlight.

3. Keep out of reach of children.

Drug-Food Interaction

1. Can be taken with or without food, though post-meal intake may reduce stomach discomfort.

2. Avoid excessive caffeine.

3. Maintain good hydration.

Interactions with Other Drugs

Inform your doctor if you are taking:

1. Antiplatelet or anticoagulant drugs (e.g., aspirin, clopidogrel, warfarin)

2. Thyroid supplements

3. Antipsychotics

4. CNS stimulants

5. Nootropic agents

6. Anticonvulsants

Combined use may require monitoring or dose modification.

Drug-Disease Interactions

Use with caution in:

1. Kidney impairment

2. Bleeding disorders

3. Severe anxiety or agitation

4. History of seizures

5. Heart rhythm disorders (rarely aggravated by stimulatory effect)

Daily Dose

Daily Dose Information of Citidolin P 500mg/400mg Tablet

Typical dose range:

1. 1 tablet once or twice daily, depending on the severity of symptoms.

2. Your doctor may adjust the dose for elderly patients or those with kidney disease.

Overdose

Overdose of Citidolin P 500mg/400mg Tablet

Symptoms may include:

1. Easily bruising or bleeding

2. Restlessness

3. Agitation

4. Severe headache

5. Nausea or vomiting

Seek immediate medical help and carry the medicine strip along.

What If You Forget to take Citidolin P 500mg/400mg Tablet?

Missed Dose of Citidolin P 500mg/400mg Tablet

1. Take as soon as you remember.

2. If it's almost time for the next dose, skip the missed one—do not double the dose.

When to contact doctor

Contact your doctor if you notice:

1. Persistent severe headache

2. Unusual bleeding or easy bruising

3. Sudden agitation or confusion

4. Severe allergic reaction

5. Vision changes

6. Difficulty sleeping lasting more than a few days

FAQ

Fact Box

Therapeutic Class

Nootropic / Neuroprotective

Disclaimer

PlatinumRx is committed to providing reliable and accurate information to support informed customer decisions. However, all information made available on the Platform, including product descriptions, comparisons, and other content, is provided solely for general informational purposes. Such information is not intended to diagnose, prevent, treat, or cure any medical condition, nor should it be relied upon as a substitute for professional medical advice, diagnosis, or treatment.

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