Levirate Injection is an anti-epileptic medicine used to treat seizures (fits) in epilepsy. It can be used alone or along with other medicines. It helps to prevent seizures for as long as you continue to take it.Levirate Injection is given as an infusion (slow drip) into a vein under the supervision of a healthcare professional. It is generally used for short-term control of seizures when treatment with oral medication is not feasible (eg. when the patient is unconscious). You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. Your doctor is likely to prescribe you oral medicines for long-term seizure control, after treatment with this injection has been completed.Some common side effects of this medicine include dizziness, headache, infection, irritation, nasopharyngitis, sleepiness, aggressive behavior, and decreased appetite. You may also experience behavioral changes, aggressive behavior, irritation, agitation, etc. Side effects are more common during the first few days and usually lessen as your body gets used to the medicine. Most of these side effects do not need medical attention, but some of them can be serious. Let your doctor know right away if you have developed an allergic reaction (hives, itching, weakness, dizziness, difficulty in breathing, or swelling of face, tongue, and throat), a skin rash, or persistent behavioral changes like confusion, forgetfulness, feeling irritable, increased aggression or hostility. There may be ways of preventing or reducing them. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse.Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. Avoid alcohol while taking this medicine, as it�may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness.� Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested periodically while taking this medicine.
Last updated on: 24-06-2025
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Levirate Injection is an anti-epileptic medicine used to treat seizures (fits) in epilepsy. It can be used alone or along with other medicines. It helps to prevent seizures for as long as you continue to take it.Levirate Injection is given as an infusion (slow drip) into a vein under the supervision of a healthcare professional. It is generally used for short-term control of seizures when treatment with oral medication is not feasible (eg. when the patient is unconscious). You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. Your doctor is likely to prescribe you oral medicines for long-term seizure control, after treatment with this injection has been completed.Some common side effects of this medicine include dizziness, headache, infection, irritation, nasopharyngitis, sleepiness, aggressive behavior, and decreased appetite. You may also experience behavioral changes, aggressive behavior, irritation, agitation, etc. Side effects are more common during the first few days and usually lessen as your body gets used to the medicine. Most of these side effects do not need medical attention, but some of them can be serious. Let your doctor know right away if you have developed an allergic reaction (hives, itching, weakness, dizziness, difficulty in breathing, or swelling of face, tongue, and throat), a skin rash, or persistent behavioral changes like confusion, forgetfulness, feeling irritable, increased aggression or hostility. There may be ways of preventing or reducing them. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse.Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. Avoid alcohol while taking this medicine, as it�may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness.� Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested periodically while taking this medicine.
Treatment of Epilepsy/Seizures
In Treatment of Epilepsy/Seizures : Levirate Injection belongs to a group of medicines called anticonvulsants (or anti-epileptics). It works by slowing down electrical signals in the brain which cause seizures (fits). This medicine can be used to control various types of seizures�myoclonic, partial-onset, and primary generalized tonic-clonic (or grand mal). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. You should continue taking it even if you feel well and are not having any seizures. Missing doses may trigger a seizure. Do not stop using this medicine until your doctor advises you.
Side effects of Levirate Infusion The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Levirate Sleepiness Dizziness Decreased appetite Fatigue Headache Behavioral changes Irritation Aggressive behavior Agitation Infection Nasopharyngitis (inflammation of the throat and nasal passages)
How to use Levirate Infusion Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Levirate Infusion works Levirate Injection is an antiepileptic medication. It works by attaching to specific sites (SV2A) on the surfaces of nerve cells. This suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause seizures.
Alcohol
Unsafe: Avoid consuming alcohol with Levirate Injection as it is deemed unsafe.
Pregnancy
Levirate Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Levirate Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.Monitor the baby for sleepiness and adequate weight gain.
Driving
Levirate Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
Levirate Injection should be used with caution in patients with kidney disease. Dose adjustment of Levirate Injection may be needed. Doctor consultation is advised.
Liver
Levirate Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Levirate Injection may not be needed in these patients. Please consult your doctor.However, a lower dose may be advised in patients with severe liver disease.
If a dose of Levirate Injection is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
It is given as IV infusion under the supervision of a doctor. Some healthy tips to prevent seizures:Take a healthy diet along with regular exercise.Practice yoga every day.Get enough sleep at nighttime.Limit the use of screen time such as mobile/ laptop.Take your medication on time. It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery. Inform your doctor if you have ever been diagnosed with kidney disease. The�dose of your medicine may need to be adjusted.
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