Methotrexate

Uses

Methotrexate is used in the treatment of rheumatoid arthritis and psoriasis.

How it Works

How Methotrexate Works Methotrexate is an immunosuppressant. In rheumatoid arthritis, it reduces the activity of the body's immune system, which decreases swelling, alleviates pain and stiffness, and improves function. In psoriasis, it slows down the rapid growth of skin cells.

Side Effects

Common side effects of Methotrexate include abdominal pain, loss of appetite, nausea, vomiting, increased liver enzymes, stomatitis (inflammation of the mouth), low blood platelets, headache, mouth ulcers, decreased white blood cell count, fatigue, diarrhea, drowsiness, throat ulcers, dyspepsia, anemia (low number of red blood cells), pneumonitis, exanthema, erythema (skin redness), and itching.

Expert Advice

Other Combinations