Aprikinin 125mg/80mg Capsule is a prescription medicine used in the treatment of nausea or vomiting experienced as a side effect of chemotherapy or anti-cancer treatment. It inhibits the signal to reach the brain that causes the feeling of nausea or vomiting.Aprikinin 125mg/80mg Capsule is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you discontinue treatment prematurely, there is a risk of symptom recurrence and worsening of your condition. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.The most common side effects are constipation, indigestion, headache, tiredness, loss of appetite, and hiccups. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Written by: Srishti Bhukta, B. Pharma
Reviewed by: Dr. Varinderjeet Kaur, MBBS
Last updated on: 24-06-2025
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Aprikinin 125mg/80mg Capsule is a prescription medicine used in the treatment of nausea or vomiting experienced as a side effect of chemotherapy or anti-cancer treatment. It inhibits the signal to reach the brain that causes the feeling of nausea or vomiting.Aprikinin 125mg/80mg Capsule is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you discontinue treatment prematurely, there is a risk of symptom recurrence and worsening of your condition. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.The most common side effects are constipation, indigestion, headache, tiredness, loss of appetite, and hiccups. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Nausea and vomiting due to chemotherapy
In Nausea and vomiting due to chemotherapy : Aprikinin 125mg/80mg Capsule blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). Take it as prescribed by the doctor to get maximum benefit.
Side effects of Aprikinin Capsule The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Aprikinin Constipation Indigestion Headache Tiredness Loss of appetite Hiccup Increased liver enzymes
How to use Aprikinin Capsule Follow your doctor's guidance regarding the dose and duration of this medication. Aprikinin 125mg/80mg Capsule can be taken it with or without food, although it's advisable to take it consistently at the same time.
How Aprikinin Capsule works Aprikinin 125mg/80mg Capsule is a combination of two different doses of Aprepitant. It works by blocking the action of a chemical messenger in the brain that may cause nausea and vomiting during treatment with anti-cancer medicines.
Alcohol
Consult your Doctor: Please consult your doctor regarding the safety of consuming alcohol with Aprikinin 125mg/80mg Capsule . Experts have not found evidence of alcohol impairing the effectiveness of the medicine.
Pregnancy
Information regarding the use of Aprikinin 125mg/80mg Capsule during pregnancy is not available. Doctor consultation is advised.
Breast feeding
Aprikinin 125mg/80mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
Aprikinin 125mg/80mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
Aprikinin 125mg/80mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Aprikinin 125mg/80mg Capsule is recommended.
Liver
Aprikinin 125mg/80mg Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aprikinin 125mg/80mg Capsule may not be needed in these patients. Please consult your doctor.
If a dose of Aprikinin 125mg/80mg Capsule is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
Aprikinin 125mg/80mg Capsule is taken alongside other medicines to help stop sickness (nausea and vomiting) after chemotherapy. Even if you do not feel like eating or drinking, try to sip water regularly to prevent you from becoming lacking in fluid in the body (dehydrated). If you are taking any contraceptive 'pill' at the same time as this medicine, the effectiveness of the 'pill' can be reduced if you have a bout of being sick (vomiting) which lasts for more than 24 hours. In such a case, ask your doctor for additional contraceptive precautions.
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